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Nevropatisk smerte er definert som smerte som oppstår som en direkte fileølge av skade eller sykdom som påvirker sentralnervesystemet, det vil si hjerne eller ryggmarg, eller det perifere nervesystemet, det vil si nervetrådene som spres til alle deler av kroppen.Han legger til at i sjeldne tilfeller kan gentleman få komplekst regional smertesy